DatabaseGHK-Cu
Tier 2–3SkinTissue RepairAnti-agingPREMIUM

GHK-Cu

Glycyl-L-Histidyl-L-Lysine Copper (GHK-Cu / Copper Tripeptide-1)
Approved without concentration limits in cosmetic formulations (US and EU). Injectable forms: FDA Category 2 bulk drug substance (2023), commercial compounding prohibited. Not a scheduled substance. No WADA listing.

For research and educational purposes only · Not medical advice · Consult a qualified physician before any human use

Profile Overview

GHK-Cu is a naturally occurring human tripeptide that declines with age and holds the strongest validated human evidence in this series for skin and wound healing applications. It is the only peptide reviewed here with mass-scale, multi-decade topical clinical use. Independent Broad Institute bioinformatic analysis found GHK tops 1,309 bioactives for reversing COPD and metastatic colon cancer gene expression, though no human trials in those domains have been conducted.

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Full Profile: Premium Members Only

The complete GHK-Cu profile includes all use cases with full evidence reviews, mechanism of action deep dive, safety analysis, evidence table, dosing guidance, and stack compatibility data.

For research and educational purposes only · Not medical advice · Consult a qualified physician before any human use